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Filtered Search Results
Biotium MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1)(2F6), CF568 conjugate, 0.1mg/mL
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination.
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Cayman Chemical 3OAcetyl2deoxygunosIn 2.7mg
An acetylated derivative of 2'-deoxycytidine-5'-triphosphate
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Cusabio Technology LLC MOUSE HEMOGLOBIN 1G
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Mouse Hemoglobin is a native protein with full length. This protein is purified from mouse erythrocytes. Its purity was determined by SDS-PAGE and reached up to 95%. It is presented the mass molecule around 14.4 kDa visualized on the gel. It has been validated in ELISA, WB and SDS-PAGE applications.Hemoglobin is the protein molecule in red blood cells involved in oxygen transport from the lung to the various peripheral tissues and returns carbon dioxide from the tissues back to the lungs. It is made up of four chains. Each of these chains contains a compound called heme, which in turn contains iron, which is what transports oxygen in the bloodstream. A healthy individual has 12 to 20 grams of hemoglobin in every 100 ml of blood.
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ABclonal Technology Calpain 1 Rabbit pAb
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The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
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Cayman Chemical 6ThIogunosIn5OtrIphosp 2.7mg
An active metabolite of 6-thioguanine and azathioprine; binds to a variety of GTPases but selectively inhibits activation of Rac1 and Rac2 over Cdc42 in primary human CD4+ T cells stimulated with anti-CD3 and anti-CD28 antibodies; inhibits T cell receptor-stimulated proliferation of T cells and reduces CD28-dependent T cell survival in vitro in isolated mouse splenocytes; increases survival in a mouse model of heart transplantation at 0.5 mg/kg
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Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Human Phospho-p53 (Ser15 & Total) Detection Kit, Control Lysate
AlphaLISA SureFire Ultra Multiplex Human Phospho-p53 (Ser15 & Total) Detection Kit, Control Lysate
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Abcam Geldanamycin, Hsp90 inhibitor, 5MG
MW 560.64 g/mol, Purity >98%. Selective Hsp90 inhibitor. Binds the ATP site of Hsp90 and inhibits chaperone activity. A benzoquinone ansamycin antibiotic. Also inhibits the Hsp90 paralog GRP94. Exhibits various cellular actions including gene expression, cell proliferation, apoptosis and angiogenesis.
The product is subject to the following: Abcam Restricted Use Statement
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Biotium Primary Antibody GFAP rGA5 CF790 1/EA
GFAP (rGA5) is a recombinant mouse monoclonal antibody that recognizes GFAP This CF790 antibody conjugate has been validated in Immunofluorescence CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness and photostability
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American Research Products Inc BoVine PentraXin related prote
BoVine PentraXin-related protein PTX3 (PTX3) ELISA kit from CUSABIO Detection Range 2 344 ng/mL-150 ng/mL Sensitivity 0 586 ng/mL Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
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ABclonal Technology Hsp90α Rabbit pAb
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The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
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Immunology Consultants anti-Human Apolipoprotein C-III Antibody (Goat) - Affinity Purified
This affinity‑purified goat antibody targets human Apolipoprotein C‑III (ApoC3), a key regulator of triglyceride metabolism and cardiovascular risk. Designed for high‑specificity detection in ELISA, Western blotting, and lipid‑metabolism research, the antibody supports studies of dyslipidemia, metabolic disease, and biomarker profiling. Its strong affinity and low nonspecific binding ensure clean, reproducible performance across diverse sample types, including serum and purified lipoprotein fractions
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Med Vet International Exel Syringe, 50-60mL, Catheter, 25/Box, 26304
Exel International 50-60mL Syringe comes with a clear barrel and easy to read graduation marks. The catheter tip is used for flushing catheters, gastostomy tubes and other devices. This quantity is 25/BX
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Abcam Elastase Inhibitor, human leukocyte elastase (HLE) inhibitor, 5MG
MW 474.9 Da, Purity >98%. Elastase Inhibitor, human leukocyte elastase (HLE) inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC Polygalaxanthone XI | 857859-82-6 | 5 MG
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Polygalaxanthone XI is a xanthone glycoside isolated from the cortexes of Polygala tenuifolia. It can be utilized in the study of expectorant and tranquilizing agents. It is intended for research use only and is not sold to patients.
- Isolated from the cortexes of Polygala tenuifolia
- Can be used in the study of expectorant and tranquilizing agents
- For research use only
- Molecular weight: 568.48
- Chemical formula: C25H28O15
- Appearance: solid, light yellow to yellow color
- Purity: 99.0%
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ABclonal Technology Fibronectin Rabbit pAb
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This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.
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